Use of Selective Serotonin Reuptake Inhibitors During Pregnancy and Risk of Congenital Cardiac Malformations ABSTRACT Background: Untreated maternal depression has been shown to have adverse effects in many children, yet how the mother should be treated is not clear and can vary with the situation. The use of selective serotonin reuptake inhibitors (SSRIs) during the first […]
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Alexander Hoffman: Risk of Congenital Ma...
Risk of Congenital Malformations With Statin Therapy During the First Trimester of Pregnancy ABSTRACT Background: Statins are the most common and effective drug used to treat hyperlipidemia. Based on animal studies showing potential teratogenic effects at high doses, statins are contraindicated in pregnancy due to concern that they would disrupt cholesterol biosynthesis for the fetus. […]