STUDENT PUBLICATIONS
Every student completes a capstone project as part of attaining their Masters of Science degree from the School of PA Studies at Pacific University, Oregon.
Each paper is published through the University’s Library CommonKnowledge resource.
To see their published work CLICK HERE
ALUMNI PUBLICATIONS
Faculty research is referenced below with links to online publications when available.
Lisa Bush, PA-C; Robert Brookshire, PA-C; Breanna Roche, PA-C; Amelia Johnson, PA-C; Frederic Cole, MD; Riyad Karmy-Jones, MD; William Long, MD; Matthew J. Martin, MD. Evaluation of Cervical Spine Clearance by Computed Tomographic Scan Alone in Intoxicated Patients With Blunt Trauma. JAMA Surg. Published online June 15, 2016. doi:10.1001/jamasurg.2016.1248.
FACULTY PUBLICATIONS
Faculty publications are referenced below with links to online publications when available.
Patrick Boyle, MD
- Boyle PJ, Keana JFW: Synthesis of pyruvate esters by the reaction of sodium pyruvate with organic halides in DMSO. J Organic Preparations and Procedures International 10:101‑102, 1978.
- Boyle PJ: Progress toward tetrodotoxin precursors. Honors Thesis, Robert Donald Clark Honors College, University of Oregon, 1978.
- Keana JFW, Boyle PJ, et al.: Synthetic intermediates potentially useful for the synthesis of tetrodotoxin and derivatives. J Organic Chemistry 48:3621‑3626, 1983.
- Cook DM, PJ Boyle: Rapid reversal of myxedema madness with triiodothyronine [Letter]. Annals of Internal Medicine 104: 893‑894, 1986.
- Boyle PJ, Schwartz NS, Shah SD, Clutter WE, Cryer PE: Plasma glucose concentrations at the onset of hypoglycemic symptoms in patients with poorly controlled diabetes and in nondiabetics. N Engl J Med 318:1487‑92, 1988.
- Boyle PJ, Liggett SB, Shah SD, Cryer PE: Direct muscarinic cholinergic inhibition of hepatic glucose production in humans. J Clin Invest 82:445‑449, 1988.
- Boyle PJ, Shah SD, Cryer PE: Insulin, glucagon, and catecholamines in prevention of hypoglycemia during fasting. Amer J Physiol 256 (Endocrinol Metab 19): E651-E661, 1989.
- Boyle PJ, Cryer PE: Growth hormone, cortisol, or both are involved in defense against, but are not critical to recovery from, hypoglycemia. Am J Physiology 260 (Endocrinol Metab 23): E395-402, 1991.
- Sharp DW, Lacy PE, Santiago JV, McCullough CS, Boyle PJ, et al. Results of our first nine intraportal islet allografts in type I, insulin dependent diabetic patients. Transplantation 51(1): 76-85, 1991.
- Hirsch IB, Boyle PJ, Craft S, Cryer PE. Higher glycemic thresholds for symptoms during adrenergic blockade in IDDM. Diabetes 40(9): 1177-1186, 1991.
- Schade DS, Boyle PJ: Insulin Resistance and Its Link to Other Syndromes. IDF Bulletin 36(3): 9-12, 1991.
- Schade DS, Boyle PJ: Insulin Resistance: Its Role in Health and Disease. Clinical Diabetes 10:3-6, 1992.
- Boyle PJ, Smith L, Avogaro A, Bier D, Shah SD, Cryer PE, Santiago JV: Absence of the dawn phenomenon and abnormal lipolysis in patients with type I diabetes and chronic growth hormone deficiency. Diabetologia 35:372-379, 1992.
- Boyle PJ, Avogaro A, Smith L, Bier D, Pappu AS, Illingworth DR, Cryer PE: Role of growth hormone in regulating nocturnal rates of lipolysis and plasma mevalonate levels in normal and diabetic humans. Am J Physiol 263 (Endocrinol Metab 26):E168-172, 1992.
- Romero KM, Butcher BA, Boyle PJ, Glew RH: Decreased renal excretion of hexosaminidase in adults with insulin-dependent diabetes mellitus with normal renal function. Clinica Chimica Acta, 216:125-133, 1993.
- Krentz AJ, Boyle PJ, Justice KM, Wright AD, Schade DS: Successful treatment of severe sulfonylurea induced hypoglycemia with octreotide. Diabetes Care 16:184-186, 1993.
- Krentz AJ, Koster FT, Crist DM, Finn F, Johnson LZ, Boyle PJ, Schade DS: Anthropometric, metabolic and immunological effects of recombinant human growth hormone in AIDS and AIDS-related complex. J AIDS 6:245-251, 1993.
- Boyle PJ, Justice K, Krentz AJ, Nagy RJ, Schade DS: Octreotide reverses hyperinsulinemia and hypoglycemia induced by oral sulfonylurea overdose. J Clin Endocrinol Metab 76(3): 752-755, 1993.
- The Diabetes Control and Complications Trial, including Boyle PJ: The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N Engl J Med 329(14): 977-986, 1993.
- Powers WJ, Boyle PJ, Hirsch IB, Cryer PE: Unaltered cerebral blood flow during hypoglycemic activation of the sympathochromaffin system in human subjects. Amer J Physiol 265(34): R883-R887, 1993.
- Hardy KJ, Burge MR, Boyle PJ, Scarpello JHB: A treatable cause for recurrent severe hypoglycaemia. Diabetes Care 177:722-724, 1994.
- Krentz AJ, Boyle PJ, Schade DS: Octreotide: a long-acting inhibitor of endogenous hormone secretion for human metabolic investigations. Metabolism 43(1): 24-31, 1994.
- Boyle PJ, Scott JC, Krentz AJ, Nagy RJ: Diminished brain glucose metabolism is a significant determinant for falling rates of systemic glucose utilization during sleep in normal man. J Clin Invest 93:529-535, 1994.
- Boyle PJ, Nagy RJ, O’Connor AM, Kempers SF, Yeo RA, Qualls C: Adaptation in brain glucose uptake following recurrent hypoglycemia. Proc Natl Acad Sci USA, 91:9352-9356, September 1994.
- Boyle PJ, Kempers SF, O’Connor AM, Nagy RJ: Brain glucose uptake and hypoglycemia unawareness in patients with insulin dependent diabetes mellitus. N Engl J Med. 333:1726-31, 1995.
- The DCCT Research Group, including Boyle PJ: Effect of intensive therapy on the development and progression of diabetic nephropathy in the Diabetes Control and Complications Trial. Kidney International. 47:1703-1720,1995.
- The DCCT Research Group, including Boyle PJ: Implementation of treatment protocols in the Diabetes Control and Complications Trial. Diabetes Care 18(3): 361-376, 1995.
- The DCCT Research Group, including Boyle PJ: The effect of intensive diabetes therapy on the development and progression of neuropathy. Annals of Internal Medicine 122(8): 561-568, 1995.
- The DCCT Research Group, including Boyle PJ: Progression of retinopathy with intensive versus conventional treatment in the Diabetes Control and Complications Trial. Ophthalmology. 102(4): 647-661, 1995.
- The DCCT Research Group, including Boyle PJ: Adverse events and their association with treatment regimens in the Diabetes Control and Complications Trial. Diabetes Care 18(11): 1415-27, 1995.
- The DCCT Research Group, including Boyle PJ: Resource utilization and costs of care in the Diabetes Control and Complications Trial. Diabetes Care 18(11): 1468-78,1995.
- Dorin RI, Field JC, Boyle PJ, Eaton RP, Icenogle MV: Insulin resistance limits glucose utilization and exercise tolerance in a patient with myophosphorylase deficiency (McArdle’s Disease). Journal of Applied Physiology 81(3): 1273-1278, 1996.
- Krentz AJ, Freedman D, Greene R, McKinley M, Boyle PJ, Schade DS: Differential effects of physiological versus pathophysiological plasma concentrations of epinephrine and norepinephrine on ketone body metabolism and hepatic portal blood flow in man. Metabolism 1214-1220, 1996.
- The DCCT Research Group, including PJ Boyle. Clustering of long-term complications in families with diabetes in the DCCT. Diabetes 46: 1829-1839, 1997.
- Boyle PJ: Alterations in brain glucose metabolism induced by hypoglycemia in man. Diabetologia, Vol 40, Suppl. 2, S69-S74, 1997.
- Morris DM, Boyle PJ, Stidley CA, Altobelli KK, Parnel T, Key C. Localized well-differentiated thyroid carcinoma: survival analysis of prognostic factors and 131I therapy. Annals of Surgical Oncology 5:329-37, 1998.
- The DCCT Research Group, including PJ Boyle. Effect of intensive therapy on residual beta-cell function in patients with type 1diabetes in the DCCT, Ann Intern Med 128:517-523, 1998.
- Valentine V, Boyle PJ, Slatton K. The Case for Case Management in a Population with Diabetes. Disease Management 2:31-36, 1999.
- Boyle PJ. Adaptations leading to hypoglycaemia in type 1 diabetes mellitus and comparison with type 2 diabetes mellitus. International Journal of Clinical Practice. 112:39-44, 2000.
- The Diabetes Prevention Group, including Boyle, PJ, Reduction in the Incidence of Type 2 Diabetes with Lifestyle Intervention or Metformin, NEJM. 346:393-403, 2002.
- Boyle PJ, King AB, Olansky L, Marchetti A, Lauy H, Magar R, Martin J. Effects of pioglitazone and rosiglitazone on blood lipid levels and glycemic control in patients with type 2 diabetes mellitus: A retrospective review of randomly selected medical records, Clinical Therapeutics, 24:35-42, 2002.
- Boyle PJ: Alterations in brain glucose uptake in the setting of hypoglycemia unawareness. Diabetes Nutrition and Metabolism, vol 15, 2002.
- Boyle PJ, Marchetti A. Treating the Spectrum of Insulin Resistance: From Beta-Cell Dysfunction to Cardiovascular Disease. Clinical Therapeutics 25 (Supplement B), 2003.
- Peters AL, Kendall DM, Buse JB, Boyle PJ, Marchetti A, Lau H. Impact of adjunctive thiazolidinedione therapy on blood lipid levels and glycemic control in patients with type 2 diabetes. Current Medical and Research Opinions, 20:215-223, January 2004.
- Lubow JM Piñón IG, Avogaro A, Cobelli C, Treeson DM, Mandeville KA, Toffolo G, and Boyle PJ. Brain oxygen utilization is unchanged by hypoglycemia in normal humans: lactate, alanine, and leucine uptake are not sufficient to offset energy deficit. Am J Physiol Endocrinol Metab, Jan 2006; 290: E149 – E153.
- Beysen C, Murphy EJ, Nagaraja H, Decaris M, Riiff T, Fong A, Hellerstein MK, Boyle PJ. A pilot study of the effects of pioglitazone and rosiglitazone on de novo lipogenesis in type 2 diabetes. J Lipid Res. 2008 Dec;49(12):2657-63. Epub 2008 Jul 18.
- Lee JJ, Powers WJ, Faulkner CB, Boyle PJ, Derdeyn CP. The Key-Schmidt technique for quantitative perfusion and oxygen metabolism measurements in the MR environment. American Journal of Neuroradiology, published online on September 20, 2012,10.3174/ajnr.A3270.
REVIEWS, EDITORIALS, AND NON-REFEREED PUBLICATIONS
- Boyle PJ: Cushing’s Disease, glucocorticoid excess, glucocorticoid deficiency and diabetes. Diabetes Reviews, 1(3): 301-308, 1993.
- Schade DS, Burge MR, Boyle PJ: It’s all in the timing. Diabetes Forecast 46(7): 32‑36, 1993.
- Boyle PJ: Glucose clamp investigations: the ups and downs, (Commentary) Diabetes Care 17(3): 239-241, 1994.
- Schade DS, Boyle PJ, Burge MR: Doctor, can you answer a question about my diabetes? Clinical Diabetes, 12(2): 27-30, 1994.
- Schade DS, Boyle PJ, Burge MR, Johannes C, Valentine V: 101 tips for improving your blood sugar. American Diabetes Association Publishing, Alexandria, VA, 1995.
- Boyle PJ: Summary and Commentary: Hierarchy of glycemic thresholds for activation of counterregulatory hormone secretion, initiation of symptoms and onset of cerebral dysfunction in normal humans. Diabetes Spectrum 7:245-247, 1994.
- Burge MR, Boyle PJ: Dietary therapy in type II diabetes mellitus. JAMA 273:898, 1995.
- Qualls C, Boyle, PJ. Hypertension Comorbidity with diabetes. New Mexico Department of Health – Diabetes Prevention Program. June 30, 2000.
- Boyle PJ, Valentine V. Diabetes Spectrum, Guest Editors: From Research to Practice, 14 (2) 1-112, 2001.
- Boyle PJ and Freeman JS, Application of Incretin Mimetics and Dipeptidyl Peptidase IV Inhibitors in Managing Type 2 Diabetes Mellitus J Am Osteopath Assoc. 2007;107(suppl 3):S10-S16.
- Boyle PJ. Diabetes mellitus and macrovascular disease: mechanisms and mediators. Am J Med. 2007 Sep;120(9 Suppl 2):S12-7.
- Boyle PJ and Zrebiec J. Management of diabetes releated hypoglycemia. South Med J Feb;100 (2): 183-94, 2007.
- Boyle PJ and Zrebiec J. Physiological and behavioral aspects of glycemic control and hypoglycemia in diabetes. South Med J 2007, Feb:100(2): 231.
- Boyle PJ, Zrebiec J. Impact of therapeutic advances on hypoglycaemia in type 2diabetes. Diabetes Metab Res Rev. 2008 May-Jun;24(4):257-85.
- Stolar MW, Hoogwerf BJ, Gorshow SM, Boyle PJ, Wales DO. Managing type 2 diabetes: going beyond glycemic control. J Manag Care Pharm. 2008 Jun;14(5 Suppl B):s2-19.
BOOKS AND BOOK CHAPTERS
- Boyle, PJ: Interrelationships between the central nervous system and peripheral glucose metabolism. In Clinical Research in Diabetes. Humana Press, 1996.
- Boyle, PJ: The Clinical Practice of Diabetes Mellitus: Hypoglycemia, 1999.
- Herbel G. Boyle PJ. (2000) Pathophysiology and treatment. Endocrinology & Metabolism Clinics of North America. 29(4):725-43.
- Edleman, S editor, Take Control of Your Diabetes, 2007, Management and Pathophysiology of Hypoglycemia.
AJ Sommers, PA-C, MS
- Sommers A, Pino MG, Davis-Risen SJ. Azithromycin for Recurrent Respiratory Tract Infections in Children: Something Old is New Again. Journal of the American Academy of Physician Assistants. Pending publication.
- Fenn DJ, Howard B, Hoxworth J, and Sommers A. Case Report: A 67 Year-Old Male with Odynophagia and Neck Pain. Journal of the American Academy of Physician Assistants. Pending publication.
- Sommers A. The Top Research of the Last Year. Conference Presentation. 2014 OSPA Fall CME: “Sea-M-E at the Beach!” October 2014.
- Sommers A. Evidence-Based Graduate Project: A Feather in Your Cap and NOT a Skeleton in Your Closet. Conference Presentation. 2013 PAEA Annual Forum. October 2013.
- Sommers A. The 5-Minute EBM Clinician. Conference Presentation. 2012 OSPA Fall CME: “Sea-M-E at the Beach!” October 2012.
- Pedemonte M, Ortiz J, Ferguson J, and Sommers A. Individual and group testing in an integrated, system-based modified-block curriculum: fostering a collaborative learning environment. The Association of Schools of Allied Health Professions. 2011 Annual Conference in Scottsdale, Az. October 19-21, 2011.
- Sommers A, Cicirello N, & Pedersen J. Fun N Fit: Group Fitness Classes for adults with Developmental Disabilities. Randomized clinical trial complete. Served as the principle investigator. 2008-2010
- Sommers, A. Description and Comparison of Pacific University Physician Assistant Program Graduates Regarding Employment, Salary/Benefits, Financial Impact of Education, and Professional Development: Analysis of Pacific University Graduate Surveys. [Master’s thesis.] Pacific University, 2004.
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