Interests

I am applied mathematician with broad interests across disciplines. I am primarily a mathematical biologist specializing in the mathematical modeling of cardiac cells, but I have led, or been involved in, investigations related to:

Click on hyperlinked topics to learn more about the projects.

*Indicates a project which has involved undergraduate students.
**Indicates a project which has involved a graduate student.

Peer-reviewed publications

  1. M. Madsen, D. Bushnell, M. Juweid, Y. Menda, M.S. O’Dorisio, T. O’Dorisio, and I. Besse. Potential Increased Tumor-Dose Delivery with Combined 131I-MIBG and 90Y-DOTATOC Treatment in Neuroendocrine Tumors: A Theoretic Model, Journal of Nuclear Medicine, 2006; 47:660-667.
  2. I. Besse, M. Madsen, D. Bushnell, M. Juweid. Modeling Combined Radiopharmaceutical Therapy: a linear optimization framework, Technology in Cancer Research and Treatment, 2009; 8(1):51-60.
  3. I. Besse, C. Mitchell, T. Hund, and E. Shibata. A computational investigation of cardiac caveolae as a source of persistent sodium current, Frontiers in Physiology, 2011; 2:87.
  4. I. Besse, and N. Rhee. A numerical method for calculating minimum distance to Near Earth Objects. Applied Mathematics and Computation, 2014; 237:274-281.

Peer-reviewed abstracts

  1. D. Bushnell, M. Madsen, T. O’dorisio, Y. Menda1, S. Muzahir, R. Ryan, I. Besse, M.S. O’dorisio. “Advantage of adding 131I MIBG to 90Y DOTATOC for treatment of patients with advanced stage neuroendocrine tumors,” J Nucl Med. 2014; 55 (Supplement 1):1429.