Interests
I am applied mathematician with broad interests across disciplines. I am primarily a mathematical biologist specializing in the mathematical modeling of cardiac cells, but I have led, or been involved in, investigations related to:
- Cardiac Electrophysiology*
- Computational Neuroscience
- Radiophamaceutical Cancer Therapy*
- Estuary Science (Biomathematics Workshop)*
- Technology in Mathematics Education**
- Celestial Mechanics
Click on hyperlinked topics to learn more about the projects.
*Indicates a project which has involved undergraduate students.
**Indicates a project which has involved a graduate student.
Peer-reviewed publications
- M. Madsen, D. Bushnell, M. Juweid, Y. Menda, M.S. O’Dorisio, T. O’Dorisio, and I. Besse. Potential Increased Tumor-Dose Delivery with Combined 131I-MIBG and 90Y-DOTATOC Treatment in Neuroendocrine Tumors: A Theoretic Model, Journal of Nuclear Medicine, 2006; 47:660-667.
- I. Besse, M. Madsen, D. Bushnell, M. Juweid. Modeling Combined Radiopharmaceutical Therapy: a linear optimization framework, Technology in Cancer Research and Treatment, 2009; 8(1):51-60.
- I. Besse, C. Mitchell, T. Hund, and E. Shibata. A computational investigation of cardiac caveolae as a source of persistent sodium current, Frontiers in Physiology, 2011; 2:87.
- I. Besse, and N. Rhee. A numerical method for calculating minimum distance to Near Earth Objects. Applied Mathematics and Computation, 2014; 237:274-281.
Peer-reviewed abstracts
- D. Bushnell, M. Madsen, T. O’dorisio, Y. Menda1, S. Muzahir, R. Ryan, I. Besse, M.S. O’dorisio. “Advantage of adding 131I MIBG to 90Y DOTATOC for treatment of patients with advanced stage neuroendocrine tumors,” J Nucl Med. 2014; 55 (Supplement 1):1429.